منابع مشابه
Staged subthalamotomy
Methods For this study, ten subjects with medication-refractory symptoms or side effects of advanced Parkinson’s disease will be enrolled. Each patient will be treated with a “sub-therapeutic” (stage 1) focused ultrasound subthalamotomy and observed for thirty days. Those who develop severe and involuntary movements, such as hemiballismus, will be excluded from the second stage procedure. For t...
متن کاملDorsal subthalamotomy for Parkinson's disease.
We report our experience of unilateral subthalamotomy in patients with Parkinson's disease (PD). Eleven patients were included in a pilot, open-labeled study to assess the effect of unilateral lesion of the subthalamic nucleus (STN) with a minimum of 12 months of follow-up. The guidelines of CAPIT (Core Assessment Program for Intracerebral Transplantation) were followed for recruitment into the...
متن کاملBilateral subthalamotomy in Parkinson's disease: initial and long-term response.
We conducted an open label pilot study of the effect of bilateral subthalamotomy in 18 patients with advanced Parkinson's disease. In seven patients, the first subthalamotomy pre-dated the second by 12-24 months ('staged surgery'). Subsequently, a second group of 11 patients received bilateral subthalamotomy on the same day ('simultaneous surgery'). Patients were assessed according to the CAPIT...
متن کاملUnilateral subthalamotomy in the treatment of Parkinson's disease.
Hyperactivity in the subthalamic nucleus (STN) is seen in animal models of Parkinson's disease, and lesioning of the STN dramatically relieves the animal's parkinsonism. Deep brain stimulation (DBS) of the STN is an effective treatment for patients with advanced Parkinson's disease. We have studied the effects of a unilateral lesion placed in the STN in predominantly hemi-parkinsonian patients....
متن کاملStaged Separations ∗
The equations and the component-specific parameters needed for these detailed models are contained in specialized programs such as Aspen. However, for preliminary work it may be sufficient, and more convenient, to employ more simplified methods. If pressures are low, we may approximate φi ≈ 1 and f 0 i ≈ P sat i (T), where P sat i (T) is the vapor pressure of pure component i. Further, if the c...
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ژورنال
عنوان ژورنال: Journal of Therapeutic Ultrasound
سال: 2015
ISSN: 2050-5736
DOI: 10.1186/2050-5736-3-s1-o6